Sunlight Affects Medicine Absorption

Sunlight. A new study shows that this can affect the dose of vitamin D levels, your doctor will prescribe certain medications. The study of metabolism and excretion is published, the first time that vitamin D levels with the ability and metabolism of drugs affect the liver disturbance. This is a difficult problem with the information of physicians and researchers to be: why patients respond differently to similar doses of the drug and the same medical records?  
Sunlight. The trial was held in the Swedish medical university Karolinska Institutet. The researchers analyzed data from 70,000 cases of immunosuppressants such as tacrolimus and sirolimus, in order to prevent transplant rejection.

Sunlight. The blood of these patients at regular intervals, so take it easy for researchers blood tests done in the winter (January to March) to launch the summer (July to September). Comparison of tacrolimus and sirolimus blood shows during the summer, higher in the winter. This means that these patients need drugs to over the summer to reach the same low dose of winter protection.

Sweden has a long winter nights and long summer, the sun and the ability to make vitamin D action in the winter and in summer very different. Sunlight and vitamin D to help with some drugs such as tacrolimus and sirolimus distribution to the liver enzyme CYP3A4. Activation.

The researchers blood samples of patients, cyclosporine, drugs for the same purpose can be collected. Between winter and summer in the great difference in height, probably as a result of CYP3A4 is not necessary for the metabolism of cyclosporine.

Although more research is needed, this study shows that CYP3A4 can provide important information on prescription. Because vitamin D is sunlight vitamin, vitamin D levels and increased UV light, it is possible, the researchers also take extra medicine to reduce the summer, but was found to move the service.

This may depend on a better control of blood as the season of certain drugs. Immunosuppressants in transplant medicine, where appropriate dosage to prevent rejection of transplanted organs is the key. As more and more people recognize the benefits of taking vitamin D, but also requires doctors to monitor drug plasma concentration.

Although more research is needed, it is the patient doses of vitamin D may affect the metabolism of certain drugs. Prospective studies should prove causation. Sunlight.

Leave a Reply

Your email address will not be published. Required fields are marked *